The present analysis revisits the impact of extremely low-frequency magnetic fields (ELF-MF) on melatonin (MLT) levels in human and rat subjects using both a parametric and non-parametric approach. In this analysis, we use 62 studies from review articles. The parametric approach consists of a Bayesian logistic regression (LR) analysis and the non-parametric approach consists of a Support Vector analysis, both of which are robust against spurious/false results. Both approaches reveal a unique well-ordered pattern, and show that human and rat studies are consistent with each other once the MF strength is restricted to cover the same range (with B ≲ 50 μT). In addition, the data reveal that chronic exposure (longer than ∼22 days) to ELF-MF appears to decrease MLT levels only when the MF strength is below a threshold of ~30 μT ( log B thr [ μ T ] = 1 . 4 - 0 . 4 + 0 . 7 ), i.e., when the man-made ELF-MF intensity is below that of the static geomagnetic field. Studies reporting an association between ELF-MF and changes to MLT levels and the opposite (no association with ELF-MF) can be reconciled under a single framework. Bioelectromagnetics. 2019;40:539-552. © 2019 Bioelectromagnetics Society.

中文翻译：

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人和大鼠的褪黑激素水平和低频磁场：贝叶斯Logistic回归的新见解。

本分析使用参数方法和非参数方法，重新审查了极低频磁场（ELF-MF）对人和大鼠受试者褪黑激素（MLT）水平的影响。在此分析中，我们使用了来自评论文章的62项研究。参数方法由贝叶斯逻辑回归（LR）分析组成，非参数方法由支持向量分析组成，这两种方法对于虚假/错误结果均具有较强的鲁棒性。两种方法都揭示了一种独特的，有序的模式，并且表明，一旦将MF强度限制在相同范围内（B）50μT），人和大鼠的研究就相互一致。此外，数据显示，仅当MF强度低于〜30μT的阈值（log B thr [μT] = 1）时，ELF-MF的慢性暴露（大于约22天）才会降低MLT水平。4-0。4 + 0。7），即当人造ELF-MF强度低于静态地磁场强度时。研究报告了ELF-MF与MLT水平变化之间的关联，而相反的情况（与ELF-MF没有关联）的研究可以在一个框架下进行核对。生物电磁学。2019; 40：539-552。©2019生物电磁学会。