Despite much research, gaps remain in knowledge about the potential health effects of exposure to radiofrequency (RF) fields. This study investigated the effects of early‐life exposure to pulsed long term evolution (LTE) 1,846 MHz downlink signals on innate mouse behavior. Animals were exposed for 30 min/day, 5 days/week at a whole‐body average specific energy absorption rate (SAR) of 0.5 or 1 W/kg from late pregnancy (gestation day 13.5) to weaning (postnatal day 21). A behavioral tracking system measured locomotor, drinking, and feeding behavior in the home cage from 12 to 28 weeks of age. The exposure caused significant effects on both appetitive behaviors and activity of offspring that depended on the SAR. Compared with sham‐exposed controls, exposure at 0.5 W/kg significantly decreased drinking frequency (P ≤ 0.000) and significantly decreased distance moved (P ≤ 0.001). In contrast, exposure at 1 W/kg significantly increased drinking frequency (P ≤ 0.001) and significantly increased moving duration (P ≤ 0.005). In the absence of other plausible explanations, it is concluded that repeated exposure to low‐level RF fields in early life may have a persistent and long‐term effect on adult behavior. Bioelectromagnetics. 2019;40:498–511. © 2019 The Authors. Bioelectromagnetics Published by Wiley Periodicals, Inc.

中文翻译：

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早期暴露于脉冲LTE射频场会导致C57BL / 6 J小鼠的活动和行为持续变化

尽管进行了大量研究，但有关暴露于射频（RF）场对健康的潜在影响的知识仍然存在差距。这项研究调查了生命早期暴露于脉冲长期演进（LTE）1,846 MHz下行链路信号对先天小鼠行为的影响。从妊娠晚期（妊娠第13.5天）到断奶（出生后第21天），动物以0.5或1 W / kg的全身平均比能量吸收率（SAR）暴露30分钟/天，5天/周。一个行为跟踪系统可以测量12到28周龄家庭笼中的运动，饮水和进食行为。暴露对依赖SAR的后代的食欲行为和活动均造成重大影响。与假暴露对照组相比，0.5 W / kg的暴露显着降低了饮酒频率（P ≤0.000）和显著下降移动的距离（P  ≤0.01）。与此相反，在曝光1W / kg的显著增加饮用频率（P  ≤0.001）和显著增加移动的持续时间（P  ≤0.005）。在没有其他合理解释的情况下，得出的结论是，在生命的早期反复接触低水平的RF场可能会对成年人的行为产生持久和长期的影响。生物电磁学。2019; 40：498–511。©2019作者。Wiley Periodicals，Inc.发布的生物电磁学