当前位置: X-MOL 学术Protein Sci. › 论文详情
Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)
SASBDB: Towards an automatically curated and validated repository for biological scattering data.
Protein Science ( IF 4.5 ) Pub Date : 2019-10-11 , DOI: 10.1002/pro.3731
Alexey G Kikhney 1 , Clemente R Borges 1 , Dmitry S Molodenskiy 1 , Cy M Jeffries 1 , Dmitri I Svergun 1
Affiliation  

Small-angle scattering (SAS) of X-rays and neutrons is a fundamental tool to study the nanostructural properties, and in particular, biological macromolecules in solution. In structural biology, SAS recently transformed from a specialization into a general technique leading to a dramatic increase in the number of publications reporting structural models. The growing amount of data recorded and published has led to an urgent need for a global SAS repository that includes both primary data and models. In response to this, a small-angle scattering biological data bank (SASBDB) was designed in 2014 and is available for public access at www.sasbdb.org. SASBDB is a comprehensive, free and searchable repository of SAS experimental data and models deposited together with the relevant experimental conditions, sample details and instrument characteristics. SASBDB is rapidly growing, and presently has over 1,000 entries containing more than 1,600 models. We describe here the overall organization and procedures of SASBDB paying most attention to user-relevant information during submission. Perspectives of further developments, in particular, with OneDep system of the Protein Data Bank, and also widening of SASBDB including new types of data/models are discussed.

中文翻译:

SASBDB:建立一个自动管理和验证的生物散射数据存储库。

X射线和中子的小角散射(SAS)是研究纳米结构特性,尤其是溶液中的生物大分子的基本工具。在结构生物学中,SAS最近从专业化转变为通用技术,导致报告结构模型的出版物数量急剧增加。记录和发布的数据量不断增长,因此迫切需要包含主要数据和模型的全球SAS存储库。为此,2014年设计了一个小角度散射生物数据库(SASBDB),可从www.sasbdb.org上公开获取。SASBDB是一个全面,免费且可搜索的SAS实验数据和模型库,以及相关的实验条件,样品详细信息和仪器特性。SASBDB正在迅速发展,目前有1000多个条目,其中包含1600多个模型。我们在此描述SASBDB的整体组织和程序,在提交过程中最注意与用户相关的信息。讨论了进一步发展的观点,尤其是蛋白质数据库的OneDep系统,以及包括新类型的数据/模型在内的SASBDB的扩展。
更新日期:2019-12-21
down
wechat
bug