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Collection of antimicrobial peptides database and its derivatives: Applications and beyond.
Protein Science ( IF 4.5 ) Pub Date : 2019-09-30 , DOI: 10.1002/pro.3714
Faiza Hanif Waghu 1 , Susan Idicula-Thomas 1
Affiliation  

Collection of antimicrobial peptides (CAMP), CAMPSign, and ClassAMP are open-access resources that have been developed to enhance research on antimicrobial peptides (AMPs). Comprehensive information on AMPs and machine learning-based predictive models are made available for users through these resources. As of date, CAMPR3 has 10,247 sequences, 757 structures, and 114 family-specific signatures of AMPs along with associated tools for AMP sequence and structure analysis. CAMPSign uses family-specific sequence conservation, in the form of patterns and hidden Markov models for identification of AMPs. ClassAMP can be used to classify AMPs as antibacterial, antifungal, or antiviral based on sequence information. Here we describe CAMP and its derivatives and illustrate, with a few examples, the contribution of these online resources to the advancement of our current understanding of AMPs.

中文翻译:

抗菌肽数据库及其衍生物的集合:应用程序及以后。

抗菌肽(CAMP),CAMPSign和ClassAMP的收集是开放资源,已开发来增强对抗菌肽(AMP)的研究。通过这些资源,用户可以获得有关AMP和基于机器学习的预测模型的全面信息。到目前为止,CAMPR3具有AMP的10,247个序列,757个结构和114个家族特定的特征以及用于AMP序列和结构分析的相关工具。CAMPSign使用特定于家族的序列保守性,以模式和隐藏的马尔可夫模型的形式来识别AMP。根据序列信息,ClassAMP可用于将AMP分类为抗菌,抗真菌或抗病毒。在这里,我们描述CAMP及其衍生物,并举例说明,
更新日期:2019-12-21
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