Platelet flow cytometry is widely used in cardiovascular medicine as the platelet surface is rich in clinical biomarkers. Surface profiling is critical in disease management, but current assays can abet clinical errors as they are suboptimal and prone to bias. Accordingly, the technical and analytical advances that can be used to create high quality assays with minimal error and maximal sensitivity were reviewed. Specifically, the best practices for instrument setup, quality control, panel design, titration, gating, and compensation were described. Adherence to these practices will enhance the validity and reliability of platelet flow cytometry in clinical/research settings. © 2019 International Clinical Cytometry Society.

中文翻译：

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血小板流式细胞术：仪器设置，控制和面板性能。

由于血小板表面富含临床生物标志物，因此血小板流式细胞术已广泛用于心血管医学。表面轮廓分析在疾病管理中至关重要，但当前的检测方法可改善临床错误，因为它们次优且容易产生偏差。因此，对可用于创建具有最小误差和最大灵敏度的高质量测定的技术和分析进展进行了综述。具体来说，描述了仪器设置，质量控制，面板设计，滴定，门控和补偿的最佳实践。遵守这些做法将提高临床/研究环境中血小板流式细胞仪的有效性和可靠性。©2019国际临床细胞计量学会。