Hepatosplenic T-cell lymphoma (HSTCL) is a very rare non-Hodgkin lymphoma with an aggressive clinical course and poor prognosis. Patients of this disease usually presented with hepatosplenomegaly, which can be misdiagnosed or delayed. Bone marrow (BM) and peripheral blood (PB) are frequently involved, however, central nervous system (CNS) involvement is less common. Here, we are reporting an unusual case of hepatosplenic γδ T-cell lymphoma in a 64-year-old man with CNS involvement. Flow cytometry immunophenotyping was proved of great diagnostic contribution. © 2018 International Clinical Cytometry Society.

中文翻译：

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具有中枢神经系统入侵的免疫功能正常男性的肝脾T细胞淋巴瘤：罕见的临床实体。

肝脾T细胞淋巴瘤（HSTCL）是一种非常罕见的非霍奇金淋巴瘤，临床病程积极，预后差。该病患者通常表现为肝脾肿大，可能被误诊或延误。骨髓（BM）和外周血（PB）经常参与，但是中枢神经系统（CNS）参与较少。在此，我们报道了一位中枢神经系统受累的64岁男性的肝脾γδT细胞淋巴瘤的不寻常病例。流式细胞仪免疫表型被证明具有重要的诊断作用。©2018国际临床细胞计量学会。