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MgSiO3 nanoparticle‐catalyzed 1,3‐dipolar cycloaddition reactions in the synthesis of novel spiroindane‐1,3‐diones derived from substituted chalcones
Journal of the Chinese Chemical Society ( IF 1.8 ) Pub Date : 2019-05-29 , DOI: 10.1002/jccs.201800445
Subramanya Gopal Hegde 1 , Lokesh Koodlur 1 , Suman Y. Reddy 2 , Manjunatha Narayanarao 3
Affiliation  

Employment of metal nanoparticles has been one of the most promising synthetic strategies for a number of chemical transformations. New spiroindane‐1,3‐diones were synthesized through [3 + 2] cycloaddition in moderate to high yields by a three‐component reaction of heterocyclic chalcone derivatives, ninhydrin, and sarcosine/L‐proline. The presence of heterogenous MgSiO3 nanoparticles (NPs) under microwave irradiation showed a robust effect in improving the yield of the desired products. Furthermore, the catalyst may be recovered and reused without significant loss of activity.

中文翻译:

MgSiO3纳米粒子催化的1,3-偶极环加成反应在取代螺l烯衍生的新型螺茚满-1,3-二酮的合成中

金属纳米颗粒的使用已成为许多化学转化中最有前途的合成策略之一。通过杂环查耳酮衍生物,茚三酮和肌氨酸/ L-脯氨酸的三组分反应,通过[3 + 2]环加成反应以中等至高收率合成了新的螺茚满-1,3-二酮。微波辐射下异质MgSiO 3纳米颗粒(NPs)的存在在提高所需产物的收率方面显示出强大的作用。此外,催化剂可被回收和再利用而没有明显的活性损失。
更新日期:2019-12-11
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