Senior-Loken syndrome (SLS) is a rare disorder primarily associated with kidney and retinal dysfunction. We generated a human induced pluripotency stem cell (hiPSC) line, designated DKHi005-A, from peripheral blood mononuclear cells of a patient with SLS using a Sendai virus reprogramming method. We confirmed that DKHi005-A cells harbor the same mutation as the patient and show a normal karyotype. DKHi005-A also has pluripotency and the capacity for differentiation into the three germ layers. This cell line is registered and available at the National Stem Cell Bank, Korea National Institute of Health.

中文翻译：

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从高级Loken综合征患者的外周血单核细胞中产生人诱导的多能干细胞。

高龄综合征（SLS）是一种罕见的疾病，主要与肾脏和视网膜功能障碍有关。我们使用仙台病毒重编程方法从SLS患者的外周血单个核细胞中生成了人诱导的多能干细胞（hiPSC）系，命名为DKHi005-A。我们确认DKHi005-A细胞具有与患者相同的突变，并显示出正常的核型。DKHi005-A还具有多能性和分化为三个细菌层的能力。该细胞系已在韩国国立卫生研究院国家干细胞库中注册并可用。