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Role of trace elements in pityriasis Alba.
Journal of Trace Elements in Medicine and Biology ( IF 3.6 ) Pub Date : 2019-10-30 , DOI: 10.1016/j.jtemb.2019.126422
Ghada M Khafagy 1 , Hanan R Nada 2 , Laila A Rashid 3 , Solwan I El-Samanoudy 2 , Eman M Abd El-Sattar 4
Affiliation  

BACKGROUND Pityriasis Alba (PA) is a common skin disorder affecting the children and it has multiple risk factors. OBJECTIVES To assess the serum levels of trace elements (copper, zinc, and magnesium) and hemoglobin (Hb) level in patients with PA. METHOD This is a case control study; 110 participants (55 cases and 55 controls) were recruited from pediatric dermatology and family medicine clinics, Cairo university hospitals. Patients were allocated into two groups, PA group (randomly selected male and female children age group (6-16) with PA lesions) and a matched control group. Full history was taken including sociodemographic data, present history of the lesions. Full general and dermatological examination was done. Blood samples were taken to asses iron and trace elements levels. The gained measures were analyzed by (SPSS) program version 22. RESULTS This study showed that Hb levels, serum ferritin, copper, zinc and magnesium were significantly lower in PA group. There was statistically significant difference between both cases and controls regarding trace elements (copper, zinc, and magnesium) with (p value was 0.000, 0.000 and 0.003) respectively. Zinc deficiency increased the risk by more than 15 folds. Also, there was statistically significant difference between both groups regarding Hb levels and serum ferritin (p value was 0.000). The reduced Hb level increases the risk of PA by more than nine folds (OR 9.6) CONCLUSION: PA is associated with reduced levels of Hb, serum zinc, ferritin, copper and magnesium; sun exposure, skin phototype were found to be important risk factors for PA.

中文翻译:

微量元素在糠疹中的作用阿尔巴。

背景技术糠疹糠疹(PA)是一种影响儿童的常见皮肤疾病,具有多种危险因素。目的评估PA患者血清中的微量元素(铜,锌和镁)和血红蛋白(Hb)水平。方法这是一个病例对照研究。从开罗大学医院的儿科皮肤科和家庭医学诊所招募了110名参与者(55例患者和55名对照)。将患者分为两组,即PA组(随机选择患有PA病变的年龄在6-16岁的男女儿童组)和一个匹配的对照组。完整的历史记录包括社会人口统计学数据,病灶的当前历史。进行了全面的皮肤病学检查。抽取血样评估铁和微量元素水平。(SPSS)程序版本22对获得的度量进行了分析。结果本研究表明,PA组的血红蛋白水平,血清铁蛋白,铜,锌和镁水平显着降低。病例和对照之间的微量元素(铜,锌和镁)的统计学差异显着(p值分别为0.000、0.000和0.003)。锌缺乏症使患病风险增加了15倍以上。此外,两组之间在血红蛋白水平和血清铁蛋白方面存在统计学差异(p值为0.000)。降低的血红蛋白水平会使患PA的风险增加9倍以上(或9.6)。结论:PA与血红蛋白,血清锌,铁蛋白,铜和镁的降低有关;暴露在阳光下,皮肤照型被发现是PA的重要危险因素。PA组的锌和镁含量显着降低。病例和对照之间的微量元素(铜,锌和镁)的统计学差异显着(p值分别为0.000、0.000和0.003)。锌缺乏症使患病风险增加了15倍以上。此外,两组之间在血红蛋白水平和血清铁蛋白方面存在统计学差异(p值为0.000)。降低的血红蛋白水平会使患PA的风险增加9倍以上(或9.6)。结论:PA与血红蛋白,血清锌,铁蛋白,铜和镁的降低有关;暴露在阳光下,皮肤照型被发现是PA的重要危险因素。PA组的锌和镁含量显着降低。病例和对照之间的微量元素(铜,锌和镁)的统计学差异显着(p值分别为0.000、0.000和0.003)。锌缺乏症使患病风险增加了15倍以上。此外,两组之间在血红蛋白水平和血清铁蛋白方面存在统计学差异(p值为0.000)。降低的血红蛋白水平会使患PA的风险增加9倍以上(或9.6)。结论:PA与血红蛋白,血清锌,铁蛋白,铜和镁的降低有关;暴露在阳光下,皮肤照型被发现是PA的重要危险因素。和镁)(p值分别为0.000、0.000和0.003)。锌缺乏症使患病风险增加了15倍以上。此外,两组之间在血红蛋白水平和血清铁蛋白方面存在统计学差异(p值为0.000)。降低的血红蛋白水平会使患PA的风险增加9倍以上(或9.6)。结论:PA与血红蛋白,血清锌,铁蛋白,铜和镁的降低有关;暴露在阳光下,皮肤照型被发现是PA的重要危险因素。和镁)(p值分别为0.000、0.000和0.003)。锌缺乏症使患病风险增加了15倍以上。此外,两组之间在血红蛋白水平和血清铁蛋白方面存在统计学差异(p值为0.000)。降低的血红蛋白水平会使患PA的风险增加9倍以上(或9.6)。结论:PA与血红蛋白,血清锌,铁蛋白,铜和镁的降低有关;暴露在阳光下,皮肤照型被发现是PA的重要危险因素。PA与Hb,血清锌,铁蛋白,铜和镁的含量降低有关;暴露在阳光下,皮肤照型被发现是PA的重要危险因素。PA与Hb,血清锌,铁蛋白,铜和镁的含量降低有关;暴露在阳光下,皮肤的照型被发现是PA的重要危险因素。
更新日期:2019-11-01
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