Glaucoma, an irreversible blinding condition affecting 3–4% adults aged above 40 years worldwide, is set to increase with a rapidly aging global population. Raised intraocular pressure (IOP) is a major risk factor for glaucoma where the treatment paradigm is focused on managing IOP using medications, laser, or surgery regimens. However, notwithstanding IOP and other clinical parameters, patient-reported outcomes, including daily functioning, emotional well-being, symptoms, mobility, and social life, remain the foremost concerns for people being treated for glaucoma. These outcomes are measured using objective patient-centered outcome measures (PCOMs) and subjective patient-reported outcome measures (PROMs). Studies using PCOMs have shown that people with glaucoma have several mobility, navigational and coordination challenges; reading and face recognition deficits; and are slower in adapting to multiple real-world situations when compared to healthy controls. Similarly, studies have consistently demonstrated, using PROMs, that glaucoma substantially and negatively impacts on peoples’ self-reported visual functioning, mobility, independence, emotional well-being, self-image, and confidence in healthcare, compared to healthy individuals, particularly in those with late-stage disease undergoing a heavy treatment regimen. The patient-centred effectiveness of current glaucoma treatment paradigms is equivocal due to a lack of well-designed randomized controlled trials; short post-treatment follow-up periods; an inappropriate selection or availability of PROMs; and/or an insensitivity of currently available PROMs to monitor changes especially in patients with newly diagnosed early-stage glaucoma. We provide a comprehensive, albeit non-systematic, critique of the psychometric properties, limitations, and recent advances of currently available glaucoma-specific PCOMs and PROMs. Finally, we propose that item banking and computerized adaptive testing methods can address the multiple limitations of paper-pencil PROMs; customize their administration; and have the potential to improve healthcare outcomes for people with glaucoma.

青光眼是一种不可逆转的致盲疾病，在全球40岁以上的成年人中有3-4％的成年人受到影响，而随着全球人口的快速老龄化，青光眼将会增加。眼内压升高（IOP）是青光眼的主要危险因素，其治疗范例主要是使用药物，激光或手术方案来管理IOP。然而，尽管有眼压和其他临床参数，患者报告的结局，包括日常功能，情绪健康，症状，活动能力和社交生活，仍然是接受青光眼治疗的人们最关注的问题。这些结果使用客观的以患者为中心的结果测量（PCOM）和主观的患者报告的结果测量（PROM）进行测量。使用PCOM进行的研究表明，青光眼患者在行动，导航和协调方面面临诸多挑战。阅读和面部识别缺陷；与健康对照相比，适应多种现实情况的速度较慢。类似地，研究一直使用PROM证明，与健康个体相比，青光眼对人们自我报告的视觉功能，活动能力，独立性，情感幸福感，自我形象以及对医疗保健的信心产生重大负面影响。患有晚期疾病的患者需接受大量治疗。由于缺乏精心设计的随机对照试验，目前以青光眼为治疗模式的以患者为中心的效果是模棱两可的。治疗后的随访时间短；PROM的选择或可用性不当；和/或当前可用的PROM对监测变化不敏感，尤其是在新诊断的早期青光眼患者中。我们提供了对心理测量特性，局限性以及当前可用的特定于青光眼的PCOM和PROM的最新进展的全面（尽管不是系统的）批评。最后，我们提出项目库和计算机化的自适应测试方法可以解决纸笔PROM的多种局限性。定制他们的管理；并有可能改善青光眼患者的医疗效果。我们建议项目银行和计算机化的自适应测试方法可以解决纸笔PROM的多个限制；定制他们的管理；并有可能改善青光眼患者的医疗效果。我们建议项目银行和计算机化的自适应测试方法可以解决纸笔PROM的多个限制；定制他们的管理；并有可能改善青光眼患者的医疗效果。