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Plant and Animal Innate Immunity Complexes: Fighting Different Enemies with Similar Weapons.
Trends in Plant Science ( IF 17.3 ) Pub Date : 2019-10-31 , DOI: 10.1016/j.tplants.2019.09.008
Glykeria Mermigka 1 , Maria Amprazi 2 , Adriani Mentzelopoulou 3 , Argyro Amartolou 3 , Panagiotis F Sarris 4
Affiliation  

Both animals and plants express intracellular innate immunity receptors known as NLR (NOD-like receptors or nucleotide-binding domain and leucine-rich repeat receptors, respectively). For various mammalian systems, the specific formation of macromolecular structures, such as inflammasomes by activated NLR receptors, has been extensively reported. However, for plant organisms, the formation of such structures was an open scientific question for many years. This year, the first plant ‘resistosome’ structure was reported, revealing significant structural similarities to mammalian apoptosome and inflammasome structures. In this review, we summarize the key components comprising the mammalian apoptosome/inflammasome structures and the newly discovered plant resistosome, highlighting their commonalities and differences.



中文翻译:

植物和动物的先天免疫复合体:用类似的武器对抗不同的敌人。

动物和植物中表达称为NLR(细胞内先天性免疫受体Ñ OD-IKE ř eceptors或ñ ucleotide结合结构域和富eucine重复ř分别)。对于各种哺乳动物系统,已经广泛报道了通过活化的NLR受体特异性形成大分子结构,例如炎性体。然而,对于植物生物体而言,多年来这种结构的形成是一个开放的科学问题。今年,首次报道了植物的“抗性体”结构,该结构与哺乳动物的细胞凋亡体和炎性体结构具有显着的结构相似性。在这篇综述中,我们总结了包括哺乳动物凋亡小体/炎症小体结构和新近发现的植物抵抗小体的关键成分,突出了它们的共性和差异。

更新日期:2019-10-31
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