In the present issue of Acta Physiologica, Jiang, et al.¹ tested how the endothelial glycocalyx transmits the blood flow shear stress to the cytoskeleton. In a series of large‐scale molecular dynamics computational experiments the dynamics of the proteoglycan syndecan‐4 force transmission is examined under varying conditions, i.e. blood flow velocity changes and proteoglycan sugar chain shedding.

中文翻译：

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Syndecan-4，一种模型蛋白聚糖，用于研究内皮糖萼的机械传感和信号转导。

在本期《生理学报》中，Jiang等人。¹测试了内皮糖萼如何将血流切应力传递到细胞骨架。在一系列大规模分子动力学计算实验中，在不同条件下（即血流速度变化和蛋白聚糖糖链脱落）检查了蛋白聚糖syndecan-4力传递的动力学。