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Looking beyond the usual suspects: sulfide stress in schizophrenia pathophysiology.
EMBO Molecular Medicine ( IF 9.0 ) Pub Date : 2019-10-29 , DOI: 10.15252/emmm.201910983
Michel Simonneau 1
Affiliation  

Schizophrenia is a complex, multifactorial disease that displays heterogeneous behavioral and cognitive syndrome (Lieberman & First, 2018). The origin of schizophrenia appears to lie in genetic and/or environmental disruption of brain development (Owen et al, 2016). In spite of current treatment that largely consists in antipsychotic drugs combined with psychological therapies, social support, and rehabilitation, developing more effective therapeutic interventions is an essential issue.

中文翻译:

超越通常的怀疑:精神分裂症病理生理中的硫化物应激。

精神分裂症是一种复杂的多因素疾病,表现出不同的行为和认知综合症(Lieberman&First,2018)。精神分裂症的起源似乎在于大脑发育的遗传和/或环境破坏(Owen等,2016)。尽管目前的治疗主要是将抗精神病药物与心理疗法,社会支持和康复相结合,但开发更有效的治疗干预措施仍是一个必不可少的问题。
更新日期:2019-12-06
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