Supercritical phase inversion was used to prepare new polymeric membranes, based on cellulose acetate and Laponite®, for tissue engineering applications. These composite membranes were characterized by a porous structure (porosity around 85%) with an average pore size ranging from about 9 to 13 μm depending on the initial weight ratio cellulose acetate/Laponite. This ratio also controlled thermal and mechanical properties of these membranes: Laponite modified membrane decomposition step and increased the membrane elasticity modulus up to 4 MPa while decreasing the percentage elongation at break from 240% to 180%. Laponite also increased material cells adhesion: thanks to its homogeneous inclusion into the membranes, a remarkable cells adhesion of around 80%, six times higher than the original material, was obtained.

超临界相转化用于制备基于醋酸纤维素和Laponite®的新型聚合物膜，用于组织工程应用。这些复合膜的特征在于其多孔结构（孔隙率大约为85％），其平均孔径范围为约9至13μm，这取决于初始乙酸纤维素/皂石的重量比。该比率还控制了这些膜的热性能和机械性能：合成皂石改性膜的分解步骤，将膜的弹性模量提高至4 MPa，同时将断裂伸长率从240％降低至180％。皂石还增加了材料细胞的粘附力：由于其均匀地包含在膜中，因此获得了80％左右的显着细胞粘附力，是原始材料的六倍。