Octoploid strawberry (Fragaria × ananassa Duch.) is a model plant for research and one of the most important non-climacteric fruit crops throughout the world. The associations between regulatory networks and metabolite composition were explored for one of the most critical agricultural properties in octoploid strawberry, fruit colour. Differences in the levels of flavonoids are due to the differences in the expression of structural and regulatory genes involved in flavonoid biosynthesis. The molecular mechanisms underlying differences in fruit colour were compared between red and white octoploid strawberry varieties. FaMYB genes had combinatorial effects in determining the red colour of fruit through the regulation of flavonoid biosynthesis in response to the increase in endogenous ABA at the final stage of fruit development. Analysis of alleles of FaMYB10 and FaMYB1 in red and white strawberry varieties led to the discovery of a white-specific variant allele of FaMYB10, FaMYB10-2. Its coding sequence possessed an ACTTATAC insertion in the genomic region encoding the C-terminus of the protein. This insertion introduced a predicted premature termination codon, which suggested the loss of intact FaMYB10 protein playing a critical role in the loss of red colour in white octoploid strawberry.

中文翻译：

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MYB 转录因子家族对八倍体草莓（Fragaria × ananassa）果实红色的控制。

八倍体草莓（Fragaria × ananassa Duch.）是一种可供研究的模式植物，也是全世界最重要的非更年期水果作物之一。对于八倍体草莓中最关键的农业特性之一，果实颜色，我们探索了调控网络和代谢物组成之间的关联。黄酮类化合物水平的差异是由于参与黄酮类生物合成的结构基因和调控基因的表达不同。比较了红色和白色八倍体草莓品种之间果实颜色差异的分子机制。FaMYB 基因通过调节类黄酮生物合成来响应果实发育最后阶段内源性 ABA 的增加，在决定果实的红色方面具有组合效应。对红色和白色草莓品种中 FaMYB10 和 FaMYB1 等位基因的分析导致发现了 FaMYB10 的白色特异性变体等位基因 FaMYB10-2。其编码序列在编码蛋白质 C 端的基因组区域中具有 ACTTATAC 插入。这种插入引入了一个预测的提前终止密码子，这表明完整的 FaMYB10 蛋白的丢失在白色八倍体草莓中红色的丧失中起关键作用。