Previous studies have observed that epilepsy risk is higher among offspring of affected women than offspring of affected men. We tested whether this “maternal effect” was present in familial epilepsies, which are enriched for genetic factors that contribute to epilepsy risk.

中文翻译：

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对癫痫风险的“母体效应”：家族性癫痫分析和先前证据的重新评估


先前的研究发现，受影响女性的后代患癫痫的风险高于受影响男性的后代。我们测试了这种“母体效应”是否存在于家族性癫痫中，家族性癫痫中富含导致癫痫风险的遗传因素。