The association between metabolic syndrome components and the development of atherosclerosis.,Journal of Human Hypertension

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The association between metabolic syndrome components and the development of atherosclerosis.
Journal of Human Hypertension ( IF 2.7 ) Pub Date : 2019-10-21 , DOI: 10.1038/s41371-019-0273-0
Anahita Aboonabi ₁ , Roselyn Rose' Meyer ₁ , Indu Singh ₁

Affiliation

Metabolic syndrome (MetS) is a collection of pathological conditions associated with metabolic, pro-inflammatory, and prothrombotic states. MetS plays an essential role in the atherosclerotic process with associated clustering of risk factors which can increase the risk of atherogenic damage. There is an association between MetS components and the progression of atherosclerosis, which is the leading cause of cardiovascular deaths. This review was undertaken to assess the potential role of metabolic syndrome components, including oxidative stress, hypertension, hyperglycaemia and insulin resistance, obesity, dyslipidemia, chronic inflammation, physical inactivity, and atherogenic diet in the progression of atherosclerosis based on existing research.

中文翻译：

代谢综合征成分与动脉粥样硬化发展之间的关联。

代谢综合征 (MetS) 是一组与代谢、促炎和促血栓状态相关的病理状况。MetS 在动脉粥样硬化过程中发挥重要作用，具有相关的危险因素聚集，可增加动脉粥样硬化损伤的风险。MetS 成分与动脉粥样硬化的进展之间存在关联，动脉粥样硬化是心血管死亡的主要原因。本综述旨在根据现有研究评估代谢综合征成分的潜在作用，包括氧化应激、高血压、高血糖和胰岛素抵抗、肥胖、血脂异常、慢性炎症、缺乏运动和致动脉粥样硬化饮食在动脉粥样硬化进展中的潜在作用。

更新日期：2019-10-22

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