In this paper we consider a method for researching the dynamics of blood flow in the cerebral cortex, on an optical phantom that reproduces the parameters of real human and mice brain structures, through the use of near and infrared ranges of laser radiation. For the investigation of real tissue we chose a laboratory mouse brain in vivo . An algorithm for non-invasive diagnostics of the degree of oxygenation was identified and optimal parameters of installation components were selected for taking information about hemodynamic indicators. Output was verified by the reference method for assessing oxygenation by degree of absorption of hemoglobin in the visible range, which indicates that data have a high correlation with classical methods. With further development, this algorithm can be used in various areas of research and diagnostics.

中文翻译：

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在各种实验模型上使用近红外光谱法评估脑组织氧合作用的动力学

在本文中，我们考虑了一种在光学模型上研究大脑皮层中血流动力学的方法，该模型通过使用近红外和红外范围的激光辐射来重现真实人类和小鼠大脑结构的参数。为了研究真实组织，我们选择了在体内的实验小鼠大脑。确定了一种用于氧合度非侵入性诊断的算法，并选择了安装组件的最佳参数以获取有关血液动力学指标的信息。通过参考方法对输出进行了验证，该参考方法通过在可见范围内血红蛋白的吸收程度来评估氧合，这表明数据与经典方法具有高度相关性。随着进一步的发展，该算法可以用于研究和诊断的各个领域。