Naringenin Exerts Cardiovascular Protective Effect in a Palmitate-Induced Human Umbilical Vein Endothelial Cell Injury Model via Autophagy Flux Improvement.,Molecular Nutrition & Food Research

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Naringenin Exerts Cardiovascular Protective Effect in a Palmitate-Induced Human Umbilical Vein Endothelial Cell Injury Model via Autophagy Flux Improvement.
Molecular Nutrition & Food Research ( IF 5.2 ) Pub Date : 2019-11-06 , DOI: 10.1002/mnfr.201900601
Qiang Zhao _{1,

2} , Hongyan Yang ₃ , Fen Liu _{1,

2} , Junyi Luo _{1,

2} , Qian Zhao _{1,

2} , Xiaomei Li _{1,

2} , Yining Yang _{1,

2}

Affiliation

Palmitic acid (PA) contributes to the pathogenesis of cardiovascular disease by promoting endothelial dysfunction, while naringenin, most abundant in oranges, has been shown to exert multiple beneficial effects on the human cardiovascular system. This study explores whether naringenin prevents PA‐induced apoptosis in human umbilical vein endothelial cells (HUVECs).

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