当前位置: X-MOL 学术J. Diabetes Investig. › 论文详情
Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)
β-Cell senescence in the pathogenesis of type 2 diabetes.
Journal of Diabetes Investigation ( IF 3.1 ) Pub Date : 2019-11-19 , DOI: 10.1111/jdi.13162
Junta Imai 1
Affiliation  

The prevalence of type 2 diabetes increases with aging, and the type 2 diabetes developing in the elderly is often accompanied by a gradual impairment of β‐cell function and reduced β‐cell mass along with aging. However, the contribution of β‐cell senescence to the pathogenesis of type 2 diabetes remains uncertain. In a recent Cell Metabolism article, Aguayo‐Mazzucato et al. described their efforts to identify the signatures of senescent β‐cells, and explored the role(s) of senescent β‐cells in type 2 diabetes.
image


中文翻译:


2 型糖尿病发病机制中的 β 细胞衰老。



2型糖尿病的患病率随着年龄的增长而增加,而老年人发生的2型糖尿病往往伴随着随着年龄的增长,β细胞功能逐渐受损,β细胞量减少。然而,β细胞衰老对2型糖尿病发病机制的贡献仍不确定。在最近的一篇《细胞代谢》文章中,Aguayo-Mazzucato等人。描述了他们为识别衰老 β 细胞特征所做的努力,并探讨了衰老 β 细胞在 2 型糖尿病中的作用。
image
更新日期:2019-11-19
down
wechat
bug