Dynamic DNA nanotechnology: toward functional nanoscale devices,Nanoscale Horizons

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Dynamic DNA nanotechnology: toward functional nanoscale devices
Nanoscale Horizons ( IF 8.0 ) Pub Date : 2019/10/15 , DOI: 10.1039/c9nh00529c
Marcello DeLuca _{1,

2,

3,

4} , Ze Shi _{4,

5,

6,

7} , Carlos E. Castro _{4,

8,

9,

10,

11} , Gaurav Arya _{1,

2,

3,

4}

Affiliation

Dynamic DNA nanotechnology involves the creation of nanoscale devices made of DNA whose primary function arises from their ability to undergo controlled motion or reconfiguration. In the past two decades, dynamic DNA nanotechnology has evolved to the point where it is now being employed in devices intended for applications in sensing, drug delivery, computation, nanorobotics, and more. In this review article, we discuss the design of dynamic DNA nanodevices and the characterization and prediction of device behavior. We also identify a number of continuing challenges in dynamic DNA nanotechnology and discuss potential solutions to those challenges.

中文翻译：

动态DNA纳米技术：面向功能纳米级设备

动态DNA纳米技术涉及创建由DNA制成的纳米级设备，其主要功能来自其进行受控运动或重新配置的能力。在过去的二十年中，动态DNA纳米技术已经发展到现在已被用于传感，药物输送，计算，纳米机器人等领域的设备中。在这篇综述文章中，我们讨论了动态DNA纳米设备的设计以及设备行为的表征和预测。我们还确定了动态DNA纳米技术中的许多持续挑战，并讨论了应对这些挑战的潜在解决方案。

更新日期：2020-02-13

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