Theranostics with simultaneous diagnosis and therapy functions are potential to greatly improve the therapeutic efficacy and reduce side effects. Fluorescence imaging has significant advantages in terms of high sensitivity, easy operation, and good biocompatibility. However, traditional fluorophores usually suffer from serious self-quenching after local accumulation at a high concentration. In contrary, the aggregation-induced emission fluorogens (AIEgens) are ideal for construction of cancer theranostics with advantages of high emission efficiency in the aggregate state. Therefore, the combination of AIEgens and different therapy modules provides a great opportunity for image-guided precise cancer treatment, which can efficiently ablate cancer cells both in vitro and in vivo. In this review, we will discuss the most recent progress of AIE-based cancer theranostics with representative examples.

具有同时诊断和治疗功能的治疗诊断学有可能极大地改善治疗效果并减少副作用。荧光成像在高灵敏度，易于操作和良好的生物相容性方面具有显着优势。然而，传统的荧光团在高浓度下局部积累后通常会遭受严重的自猝灭。相反，聚集诱导的发射氟（AIEgen）是构建癌症治疗药物的理想选择，其优点是在聚集状态下具有高发射效率。因此，AIEgens和不同治疗模块的组合为图像引导的精确癌症治疗提供了巨大的机会，可以在体内和体外有效消融癌细胞。在这篇评论中，