In this issue of Cancer Cell, Burr et al. report that PRC2 plays a conserved role in silencing antigen presentation and processing genes and, in turn, CD8+ T cell activation. Furthermore, PRC2-targeted therapeutics overcome gene silencing and promote tumor clearance by cytotoxic T cells.

中文翻译：

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PRC2通过MHC-1和CD8 + T细胞发出红光，绿光。

在本期《癌细胞》中，Burr等人。报告指出，PRC2在沉默抗原呈递和加工基因以及CD8 + T细胞活化中起着保守的作用。此外，靶向PRC2的疗法克服了基因沉默，并通过细胞毒性T细胞促进了肿瘤清除。