Optimal stimulation frequency for vibrational optical coherence elastography.,Journal of Biophotonics

当前位置： X-MOL 学术 › J. Biophotonics › 论文详情

Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)

Optimal stimulation frequency for vibrational optical coherence elastography.
Journal of Biophotonics ( IF 2.0 ) Pub Date : 2019-11-25 , DOI: 10.1002/jbio.201960066
Duo Zhang ₁ , Jinjiang Wang ₂ , Chunhui Li ₁ , Zhihong Huang ₁

Affiliation

Vibrational optical coherence elastography (OCE) is a promising tool for extracting the mechanical property of soft tissue. Purpose of this study is focusing on settling the optimal frequency range for vibrational OCE with evenly distributed stress filed. A finite element model of 2% agar phantom was built by ANSYS with a vibration stimulation frequency range from 200 to 3000 Hz. Practical experiments were carried out for cross‐validation with the same frequencies and sample. Lateral and horizontal stress filed distributions under different frequencies were mathematically evaluated by coefficient of variance and degree of linearity. Results from simulation and practical experiment cross‐validated each other and 1000 Hz was set as the maximum ideal frequency for vibrational OCE, while the minimum frequency is set by theoretical calculation with a result of 250 Hz. An ex vivo biological sample was utilised to testify performance of vibrational OCE with excitation frequencies in and out of concluded optimal range, which showed that stiffness was better mapped out in optimal frequency range.

中文翻译：

振动光学相干弹性成像的最佳刺激频率。

振动光学相干弹性成像（OCE）是提取软组织机械特性的有前途的工具。这项研究的目的是着重于建立应力均匀分布的振动OCE的最佳频率范围。ANSYS建立了2％琼脂幻影的有限元模型，其振动刺激频率范围为200至3000 Hz。进行了相同频率和样品交叉验证的实用实验。通过方差系数和线性度，通过数学方法评估了不同频率下的横向和横向应力场分布。来自仿真和实际实验的结果相互交叉验证，并且将1000 Hz设置为振动OCE的最大理想频率，而最小频率是通过理论计算设置的，结果为250 Hz。体外生物样品被用于验证振动OCE的性能，该振动OCE的激发频率在最终最佳范围之内和之外，这表明在最佳频率范围内更好地标明了刚度。

更新日期：2019-11-25

点击分享查看原文

点击收藏

阅读更多本刊最新论文本刊介绍/投稿指南11