Excision of both pretreatment marked positive nodes and sentinel nodes improves axillary staging after neoadjuvant systemic therapy in breast cancer,British Journal of Surgery

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Excision of both pretreatment marked positive nodes and sentinel nodes improves axillary staging after neoadjuvant systemic therapy in breast cancer
British Journal of Surgery ( IF 8.6 ) Pub Date : 2019-10-08 , DOI: 10.1002/bjs.11320
J M Simons _{1,

2} , M L M A van Pelt ₃ , A W K S Marinelli ₃ , M E Straver ₃ , A M Zeillemaker ₄ , L M Pereira Arias-Bouda _{5,

6} , T J A van Nijnatten ₇ , L B Koppert ₁ , K K Hunt ₈ , M L Smidt _{9,

10} , E J T Luiten ₁₁ , C C van der Pol _{2,

4}

Affiliation

Department of Surgical Oncology, Erasmus Medical Centre Rotterdam, Rotterdam, the Netherlands.
Department of Surgical Oncology, University Medical Centre Utrecht, Utrecht University, Utrecht, the Netherlands.
Department of Surgical Oncology, Haaglanden Medical Centre, The Hague, the Netherlands.
Department of Surgical Oncology, Alrijne Hospital, Leiderdorp, the Netherlands.
Department of Nuclear Medicine, Alrijne Hospital, Leiderdorp, the Netherlands.
Section of Nuclear Medicine, Department of Radiology, Leiden University Medical Centre, Leiden, the Netherlands.
Department of Radiology and Nuclear Medicine, Maastricht University Medical Centre+, Maastricht, the Netherlands.
Department of Breast Surgical Oncology, University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
Department of Surgical Oncology, Maastricht University Medical Centre+, Maastricht, the Netherlands.
GROW - School for Oncology and Developmental Biology, Maastricht University Medical Centre+, Maastricht, the Netherlands.
Department of Surgical Oncology, Amphia Hospital, Breda, the Netherlands.

Marking the axilla with radioactive iodine seed and sentinel lymph node (SLN) biopsy have been proposed for axillary staging after neoadjuvant systemic therapy in clinically node‐positive breast cancer. This study evaluated the identification rate and detection of residual disease with combined excision of pretreatment‐positive marked lymph nodes (MLNs) together with SLNs.

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