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The risk of overweight and obesity in children with autism spectrum disorders: A systematic review and meta-analysis.
Obesity Reviews ( IF 8.0 ) Pub Date : 2019-10-08 , DOI: 10.1111/obr.12933
Chanaka N Kahathuduwa 1, 2, 3, 4 , Blake D West 1, 5 , Jessica Blume 1, 5 , Nagaraju Dharavath 1 , Naima Moustaid-Moussa 4, 6, 7 , Ann Mastergeorge 1, 5
Affiliation  

Multiple studies have suggested that autism spectrum disorders seem to increase the risk of overweight and obesity. We examined the pooled prevalence and relative risk of developing overweight or obesity among children with autism spectrum disorders in a systematic review and meta‐analysis. We searched PubMed, Scopus, ProQuest, and Web of Science databases and subsequently screened the records to identify studies that reported prevalence of overweight and/or obesity in children with ASD and matched groups of neurotypical children. DerSimonian‐Laird random‐effects meta‐analyses were performed to examine pooled prevalence and relative risk of obesity in children with autism spectrum disorders using the “meta” package in R software. Among children with autism spectrum disorders, the prevalence of obesity was 22.2%. Children with ASD had a 41.1% greater risk (P = .018) of development of obesity. Non‐Caucasian race, increasing age, female sex, and living in the United States emerged as positive moderators of the association between autism spectrum disorders and prevalence of overweight or obesity. Autism spectrum disorders seem to increase the risk of childhood obesity. Increased awareness of this association may allow the implementation of early interventions to reduce obesity and prevent potential deterioration of quality‐of‐life in this population.

中文翻译:

自闭症谱系障碍儿童超重和肥胖的风险:系统评价和荟萃分析。

多项研究表明,自闭症谱系障碍似乎增加了超重和肥胖的风险。我们通过系统的回顾和荟萃分析,检查了自闭症谱系障碍儿童的合并患病率和患超重或肥胖的相对风险。我们搜索了PubMed,Scopus,ProQuest和Web of Science数据库,随后筛选了记录,以鉴定报告了ASD儿童和神经型典型儿童的超重和/或肥胖患病率的研究。使用R软件中的“ meta”软件包,对DerSimonian-Laird随机效应荟萃分析进行了分析,以检查自闭症谱系障碍儿童的合并患病率和肥胖症相对风险。在患有自闭症谱系障碍的儿童中,肥胖症的患病率为22.2%。患有自闭症的儿童有41岁。P = .018)肥胖的发展。非高加索人种,年龄增长,女性和在美国生活成为自闭症谱系障碍与超重或肥胖患病率之间联系的积极调节者。自闭症谱系障碍似乎增加了儿童肥胖的风险。对这种联系的认识的提高可以允许早期干预措施的实施,以减少肥胖症并防止该人群的生活质量潜在恶化。
更新日期:2019-10-08
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