Microtubules are core components of the cytoskeleton and serve as tracks for motor protein-based intracellular transport. Microtubule networks are highly diverse across different cell types and are believed to adapt to cell type-specific transport demands. Here we review how the spatial organization of different subsets of microtubules into higher-order networks determines the traffic rules for motor-based transport in different animal cell types. We describe the interplay between microtubule network organization and motor-based transport within epithelial cells, oocytes, neurons, cilia, and the spindle apparatus.

中文翻译：

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细胞物流：揭示微管组织和细胞内运输之间的相互作用。

微管是细胞骨架的核心成分，并充当基于运动蛋白的细胞内转运的轨道。微管网络在不同的细胞类型之间差异很大，据信可以适应特定于细胞类型的运输需求。在这里，我们回顾了微管的不同子集进入高阶网络的空间组织如何确定不同动物细胞类型中基于运动的运输的交通规则。我们描述了微管网络组织和上皮细胞，卵母细胞，神经元，纤毛和纺锤体中基于运动的运输之间的相互作用。