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Screening for differentiated thyroid cancer in selected populations.
The Lancet Diabetes & Endocrinology ( IF 44.0 ) Pub Date : 2019-10-04 , DOI: 10.1016/s2213-8587(19)30324-9
Livia Lamartina 1 , Giorgio Grani 2 , Cosimo Durante 2 , Sebastiano Filetti 2 , David S Cooper 3
Affiliation  

The main purpose of cancer screening programmes should not be to detect all cancers, but to discover potentially fatal or clinically relevant cancers. The US Preventive Services Task Force recommends against screening for thyroid cancer in the general, asymptomatic adult population, as such screening would result in harms that outweigh any potential benefits. This recommendation does not apply to patients with symptoms or to individuals at increased risk of thyroid cancer because of a history of exposure to ionising radiation (in childhood, as radioactive fallout, or in medical treatment as low-dose radiotherapy for benign conditions or high-dose radiation for malignancy), inherited genetic syndromes associated with thyroid cancer (eg, familial adenomatous polyposis), or one or more first-degree relatives with a history of thyroid cancer. We discuss the evidence for and against screening individuals who are at high risk, and consider the different screening tools available.

中文翻译:

在特定人群中筛查分化型甲状腺癌。

癌症筛查程序的主要目的不应是检测所有癌症,而应发现潜在的致命或临床相关癌症。美国预防服务工作队建议不要对无症状的普通成年人进行甲状腺癌的筛查,因为这种筛查所带来的危害将超过任何潜在的好处。该建议不适用于因暴露于电离辐射史而出现症状的患者或患有甲状腺癌风险较高的个体(在儿童时期,作为放射性辐射,或在医学治疗中,对于良性疾病或高剂量的低剂量放疗)剂量辐射以治疗恶性肿瘤),与甲状腺癌相关的遗传遗传综合征(例如家族性腺瘤性息肉病)或一个或多个具有甲状腺癌病史的一级亲属。
更新日期:2019-12-18
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