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Suppressed fate.
Nature Reviews Cancer ( IF 72.5 ) Pub Date : 2019-10-02 , DOI: 10.1038/s41568-019-0215-8
Anna Dart 1
Affiliation  

Morris IV et al. adapted a mouse model of human pancreatic ductal adenocarcinoma and found that p53-dependent metabolic changes restrain tumour progression through α-ketoglutarate accumulation and promotion of a premalignant cell fate.

中文翻译:

压制命运。

莫里斯四世等人。适应了人类胰腺导管腺癌的小鼠模型,发现 p53 依赖性代谢变化通过 α-酮戊二酸积累和促进癌前细胞命运来抑制肿瘤进展。
更新日期:2019-10-02
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