Promoted by recent advances in developing nanomaterials and drug delivery, stimuli-responsive polymer systems that can remotely trigger drug release in a spatiotemporal manner has attracted significant attention in biotechnology. Implementation of remote-controlled release requires functional polymers to be susceptible to specific physical and/or chemical stimuli. In this minireview, we focus on the recent advances in the construction of stimuli-responsive polymer systems for remotely controlling drug release in response to an externally applied stimulus (light, microwave, magnetic field, electric field and ultrasound). The design of the stimuli-responsive polymer systems and formulations to remotely control the release of drug molecules is also highlighted in this minireview. Furthermore, the potential in biomedical applications and the perspectives of future developments of these stimuli-responsive polymer systems are also briefly discussed.

在开发纳米材料和药物输送的最新进展的推动下，可以以时空方式远程触发药物释放的刺激响应性聚合物系统在生物技术领域引起了广泛的关注。遥控释放的实现要求功能性聚合物易于受到特定的物理和/或化学刺激。在此小型审查中，我们重点关注刺激响应性聚合物系统的构建方面的最新进展，以响应外部施加的刺激（光，微波，磁场，电场和超声）来远程控制药物释放。在本微型综述中，还着重介绍了可远程控制药物分子释放的刺激响应性聚合物系统和制剂的设计。此外，