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GWAS Atlas: a curated resource of genome-wide variant-trait associations in plants and animals.
Nucleic Acids Research ( IF 16.6 ) Pub Date : 2020-01-08 , DOI: 10.1093/nar/gkz828
Dongmei Tian 1, 2 , Pei Wang 1, 2, 3 , Bixia Tang 1, 2 , Xufei Teng 1, 2, 3 , Cuiping Li 1, 2 , Xiaonan Liu 1, 2, 4 , Dong Zou 1, 2 , Shuhui Song 1, 2, 3, 5 , Zhang Zhang 1, 2, 3, 4, 5
Affiliation  

GWAS Atlas (https://bigd.big.ac.cn/gwas/) is a manually curated resource of genome-wide variant-trait associations for a wide range of species. Unlike existing related resources, it features comprehensive integration of a high-quality collection of 75 467 variant-trait associations for 614 traits across 7 cultivated plants (cotton, Japanese apricot, maize, rapeseed, rice, sorghum and soybean) and two domesticated animals (goat and pig), which were manually curated from 254 publications. We integrated these associations into GWAS Atlas and presented them in terms of variants, genes, traits, studies and publications. More importantly, all associations and traits were annotated and organized based on a suite of ontologies (Plant Trait Ontology, Animal Trait Ontology for Livestock, etc.). Taken together, GWAS Atlas integrates high-quality curated GWAS associations for animals and plants and provides user-friendly web interfaces for data browsing and downloading, accordingly serving as a valuable resource for genetic research of important traits and breeding application.

中文翻译:

GWAS Atlas:精选的动植物全基因组变异性状关联资源。

GWAS Atlas(https://bigd.big.ac.cn/gwas/)是人工策划的,适用于广泛物种的全基因组变异性状关联的资源。与现有的相关资源不同,它具有高质量的75 467个变异性状关联的全面集成,这些变异性状涵盖7种栽培植物(棉花,日本杏,玉米,油菜籽,水稻,高粱和大豆)和两种家养动物(614种)的614个性状。山羊和猪),它们是从254种出版物中手动策划的。我们将这些关联整合到了GWAS Atlas中,并按照变体,基因,特征,研究和出版物进行了介绍。更重要的是,所有关联和特征都基于一套本体(植物性状本体,牲畜的动物性状本体等)进行注释和组织。在一起
更新日期:2020-01-06
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