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Halloysite Nanoclay/Biopolymers Composite Materials in Tissue Engineering.
Biotechnology Journal ( IF 3.2 ) Pub Date : 2019-11-05 , DOI: 10.1002/biot.201900055
Ekaterina Naumenko 1 , Rawil Fakhrullin 1
Affiliation  

Biocompatible materials for the fabrication of tissue substitutes are crucially important in the advancement of modern medicinal biotechnology. These materials, to serve their function, should be similar in physical, chemical, biological, and structural properties to native tissues which they are aimed to mimic. The porosity of artificial scaffolds is essential for normal nutrient transmission to cells, gas diffusion, and cell attachment and proliferation. Nanoscale inorganic additives and dopants are widely used to improve the functional properties of the polymer materials for tissue engineering. Among these inorganic dopants, halloysite nanotubes are arguably the most perspective candidates because of their biocompatibility and functional properties allowing to enhance significantly the mechanical and chemical stability of tissue engineering scaffolds. Here, this vibrant field of biotechnology for regenerative medicine is overviewed.

中文翻译:

组织工程中的埃洛石纳米粘土/生物聚合物复合材料。

用于制造组织替代物的生物相容性材料在现代医学生物技术的发展中至关重要。为了发挥功能,这些材料应在物理,化学,生物学和结构特性上与拟模仿的天然组织相似。人工支架的孔隙率对于正常营养物向细胞的传输,气体扩散以及细胞的附着和增殖至关重要。纳米级无机添加剂和掺杂剂被广泛用于改善用于组织工程的聚合物材料的功能特性。在这些无机掺杂剂中,埃洛石纳米管可以说是最有前景的候选物,因为它们的生物相容性和功能特性可以显着提高组织工程支架的机械和化学稳定性。在此,对再生医学生物技术这个充满生机的领域进行了概述。
更新日期:2019-11-06
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