Lung cancer and cardiovascular disease (CVD) are both leading causes of mortality and morbidity in the UK and worldwide.1 2 Every day in the UK, approximately 130 people learn that they have lung cancer, and nearly 100 die because of it.3 For CVD, the numbers are even greater; on average, 460 people die each day due to it.4 These are pause for thought statistics that are a call to action for evidence-based public health initiatives that make a difference. In early 2019, NHS England rolled out its targeted screening programme for lung cancer with low-radiation dose CT. At an estimated cost of £70 million, 10 regional community lung health check projects are planned, starting in areas with greatest lung cancer death rates and targeting high-risk individuals.5 6 Central to this initiative was the Macmillan funded Manchester study, which targeted these hard to reach individuals in the community as opposed to established healthcare settings. Health economics analysis indicated this approach was cost-effective, with high rates of early-stage lung cancer detection, which were amenable to radical treatments.7 8 There is ongoing debate, however, about the relative merits of a national targeted lung cancer screening project, particularly in the setting of an already overstretched NHS.9 To this end, rigorous audit and governance of the programme are crucial.5 Interestingly, alongside lung cancer detection, several lung cancer screening studies have also shown their study cohorts are at high risk of CVD.10–12 In this issue of the journal, …

中文翻译：

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靶向肺癌筛查是解决心血管风险的好时机吗？

肺癌和心血管疾病 (CVD) 都是英国和全世界死亡和发病的主要原因。1 2 在英国，每天约有 130 人得知他们患有肺癌，近 100 人因此死亡。3 对于CVD，数字甚至更大；平均而言，每天有 460 人因此而死亡。4 这些是思想统计数据的暂停，这些数据呼吁采取行动，以循证公共卫生举措发挥作用。2019 年初，英国 NHS 推出了低辐射剂量 CT 肺癌靶向筛查计划。预计耗资 7000 万英镑，计划开展 10 个区域社区肺部健康检查项目，从肺癌死亡率最高的地区开始，针对高危人群。5 6 该计划的核心是麦克米伦资助的曼彻斯特研究，它针对的是社区中这些难以接触到的个人，而不是既定的医疗保健机构。卫生经济学分析表明，这种方法具有成本效益，早期肺癌检测率高，适合根治性治疗。7 8 然而，关于国家靶向肺癌筛查项目的相对优点一直存在争议，尤其是在 NHS 已经不堪重负的情况下。9 为此，对该计划的严格审计和治理至关重要。5 有趣的是，除了肺癌检测外，几项肺癌筛查研究还表明，他们的研究队列处于高风险中CVD.10-12 在本期杂志中，……