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Clinical utility of an increase in magnetic resonance elastography in predicting fibrosis progression in NAFLD
Hepatology ( IF 13.5 ) Pub Date : 2020-01-27 , DOI: 10.1002/hep.30974
Veeral H Ajmera 1, 2 , Amy Liu 1 , Seema Singh 1 , Georg Yachoa 1 , Matthew Ramey 1 , Meera Bhargava 1 , Ava Zamani 1 , Scarlett Lopez 1 , Neeraj Mangla 1 , Ricki Bettencourt 1 , Emily Rizo 1 , Mark Valasek 3 , Cynthia Behling 4 , Lisa Richards 1 , Claude Sirlin 5 , Rohit Loomba 1, 2
Affiliation  

Cross‐sectional studies have shown that magnetic resonance elastography (MRE) is accurate in the noninvasive detection of advanced fibrosis in nonalcoholic fatty liver disease (NAFLD). However, there are limited data on the longitudinal association between an increase in liver stiffness on MRE and fibrosis progression in NAFLD. Therefore, using a well‐characterized prospective cohort of patients with biopsy‐proven NAFLD, we aimed to examine the longitudinal association between a 15% increase in liver stiffness on MRE and fibrosis progression in NAFLD.

中文翻译:

增加磁共振弹性成像在预测 NAFLD 纤维化进展中的临床效用

横断面研究表明,磁共振弹性成像 (MRE) 在非酒精性脂肪性肝病 (NAFLD) 晚期纤维化的无创检测中是准确的。然而,关于 MRE 肝脏硬度增加与 NAFLD 纤维化进展之间纵向关联的数据有限。因此,我们使用一个特征明确的前瞻性队列活检证实的 NAFLD 患者,旨在检查 MRE 肝硬度增加 15% 与 NAFLD 纤维化进展之间的纵向关联。
更新日期:2020-01-27
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