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Alliance of Genome Resources Portal: unified model organism research platform.
Nucleic Acids Research ( IF 16.6 ) Pub Date : 2020-01-08 , DOI: 10.1093/nar/gkz813
, Julie Agapite , Laurent-Philippe Albou , Suzi Aleksander , Joanna Argasinska , Valerio Arnaboldi , Helen Attrill , Susan M Bello , Judith A Blake , Olin Blodgett , Yvonne M Bradford , Carol J Bult , Scott Cain , Brian R Calvi , Seth Carbon , Juancarlos Chan , Wen J Chen , J Michael Cherry , Jaehyoung Cho , Karen R Christie , Madeline A Crosby , Jeff De Pons , Mary E Dolan , Gilberto dos Santos , Barbara Dunn , Nathan Dunn , Anne Eagle , Dustin Ebert , Stacia R Engel , David Fashena , Ken Frazer , Sibyl Gao , Felix Gondwe , Josh Goodman , L Sian Gramates , Christian A Grove , Todd Harris , Marie-Claire Harrison , Douglas G Howe , Kevin L Howe , Sagar Jha , James A Kadin , Thomas C Kaufman , Patrick Kalita , Kalpana Karra , Ranjana Kishore , Stan Laulederkind , Raymond Lee , Kevin A MacPherson , Steven J Marygold , Beverley Matthews , Gillian Millburn , Stuart Miyasato , Sierra Moxon , Hans-Michael Mueller , Christopher Mungall , Anushya Muruganujan , Tremayne Mushayahama , Robert S Nash , Patrick Ng , Michael Paulini , Norbert Perrimon , Christian Pich , Daniela Raciti , Joel E Richardson , Matthew Russell , Susan Russo Gelbart , Leyla Ruzicka , Kevin Schaper , Mary Shimoyama , Matt Simison , Cynthia Smith , David R Shaw , Ajay Shrivatsav , Marek Skrzypek , Jennifer R Smith , Paul W Sternberg , Christopher J Tabone , Paul D Thomas , Jyothi Thota , Sabrina Toro , Monika Tomczuk , Marek Tutaj , Monika Tutaj , Jose-Maria Urbano , Kimberly Van Auken , Ceri E Van Slyke , Shur-Jen Wang , Shuai Weng , Monte Westerfield , Gary Williams , Edith D Wong , Adam Wright , Karen Yook

The Alliance of Genome Resources (Alliance) is a consortium of the major model organism databases and the Gene Ontology that is guided by the vision of facilitating exploration of related genes in human and well-studied model organisms by providing a highly integrated and comprehensive platform that enables researchers to leverage the extensive body of genetic and genomic studies in these organisms. Initiated in 2016, the Alliance is building a central portal (www.alliancegenome.org) for access to data for the primary model organisms along with gene ontology data and human data. All data types represented in the Alliance portal (e.g. genomic data and phenotype descriptions) have common data models and workflows for curation. All data are open and freely available via a variety of mechanisms. Long-term plans for the Alliance project include a focus on coverage of additional model organisms including those without dedicated curation communities, and the inclusion of new data types with a particular focus on providing data and tools for the non-model-organism researcher that support enhanced discovery about human health and disease. Here we review current progress and present immediate plans for this new bioinformatics resource.

中文翻译:

基因组资源门户联盟:统一模式生物研究平台。

基因组资源联盟 (Alliance) 是主要模式生物数据库和基因本体的联盟,其愿景是通过提供一个高度集成和全面的平台,促进人类和经过充分研究的模式生物中相关基因的探索。使研究人员能够利用这些生物体中广泛的遗传和基因组研究。该联盟于 2016 年启动,正在建立一个中央门户网站 (www.alliancegenome.org),用于访问主要模式生物的数据以及基因本体数据和人类数据。联盟门户中表示的所有数据类型(例如基因组数据和表型描述)都有共同的数据模型和管理工作流程。所有数据都是开放的,可通过各种机制免费获得。联盟项目的长期计划包括关注其他模式生物的覆盖范围,包括那些没有专门管理社区的模式生物,以及纳入新的数据类型,特别关注为支持支持的非模式生物研究人员提供数据和工具加强对人类健康和疾病的发现。在这里,我们回顾了当前的进展,并提出了这个新的生物信息学资源的近期计划。
更新日期:2020-01-06
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