This study aimed to estimate the productive and economic impacts caused by the withdrawal of antibiotic growth promoters (AGP) from broilers diet. Indexed publications that compared diets with or without AGP (AGP+/AGP-) for broilers (from initial to final phase) were collected and the results of feed intake, weight gain, and feed conversion were compiled in a database. A meta-analysis was performed following sequential analyses: graphical approach (to observe biological data coherence), correlation (to identify related factors), and variance-covariance (to compare groups). The annual number of broiler slaughtered in Brazil, target weight gain and feed conversion for each phase, the variation in feed conversion, feed cost, and AGP costs were used to build a model to estimate the effects of the AGP withdrawal on feeding costs. The database comprised 174 scientific articles containing 183 experiments, totaling 121,643 broilers, most of which were Ross (52% of the studies). The most frequent AGP sources/forms in the database were Avilamycin (41% of the AGP+ treatments), Flavomycin (19%), Virginiamycin (16%), and Bacitracin (14%). Higher feed intake, weight gain, and lower feed conversion were attributed (P < 0.05) to AGP+ diets during Initial phase (1 to 21 D). In Final phase (22 to 42 D) no differences were observed in performance variables. Treatments AGP+ presented higher weight gain and better feed conversion in the Total period (1 to 42 D). The results of feed conversion were improved (P < 0.05) with Avilamycin and Flavomycin; Virginiamycin improved weight gain and feed conversion. In the Total period, the economic impact was $0.03 per animal and a total of $183,560,232 per year. It was concluded that broilers fed AGP+ diets have higher weight gain and better feed conversion than those fed AGP- diets, and withdrawing AGP increases production costs.

中文翻译：

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从肉鸡日粮中去除抗生素生长促进剂：性能指标和经济影响。

本研究旨在评估从肉鸡日粮中停用抗生素生长促进剂 (AGP) 对生产和经济的影响。收集了比较有或无 AGP (AGP+/AGP-) 的肉鸡日粮（从初始阶段到最后阶段）的索引出版物，并将采食量、增重和饲料转化率的结果汇总到数据库中。在顺序分析之后进行荟萃分析：图形方法（观察生物学数据的一致性）、相关性（识别相关因素）和方差协方差（比较组）。巴西的年屠宰肉鸡数量、每个阶段的目标增重和饲料转化率、饲料转化率的变化、饲料成本和 AGP 成本被用来建立一个模型来估计 AGP 退出对饲养成本的影响。该数据库包含 174 篇科学文章，包含 183 个实验，总计 121,643 只肉鸡，其中大部分是罗斯（占研究的 52%）。数据库中最常见的 AGP 来源/形式是阿维拉霉素（AGP+ 治疗的 41%）、黄霉素（19%）、弗吉尼亚霉素（16%）和杆菌肽（14%）。较高的采食量、增重和较低的饲料转化率（P < 0.05）归因于初始阶段（1 至 21 天）的 AGP+ 日粮。在最后阶段（22 到 42 D），在性能变量中没有观察到差异。AGP+ 处理在总期（1 至 42 日）中表现出更高的增重和更好的饲料转化率。阿维拉霉素和黄霉素提高了饲料转化率（P < 0.05）；维吉尼亚霉素提高了体重增加和饲料转化率。在整个期间，经济影响为 0 美元。每只动物 03 美元，每年总计 183,560,232 美元。得出的结论是，与饲喂 AGP+ 日粮的肉鸡相比，饲喂 AGP+ 日粮的肉鸡具有更高的增重和更好的饲料转化率，并且停用 AGP 会增加生产成本。