Gephebase is a manually-curated database compiling our accumulated knowledge of the genes and mutations that underlie natural, domesticated and experimental phenotypic variation in all Eukaryotes-mostly animals, plants and yeasts. Gephebase aims to compile studies where the genotype-phenotype association (based on linkage mapping, association mapping or a candidate gene approach) is relatively well supported. Human clinical traits and aberrant mutant phenotypes in laboratory organisms are not included and can be found in other databases (e.g. OMIM, OMIA, Monarch Initiative). Gephebase contains more than 1700 entries. Each entry corresponds to an allelic difference at a given gene and its associated phenotypic change(s) between two species or two individuals of the same species, and is enriched with molecular details, taxonomic information, and bibliographic information. Users can easily browse entries and perform searches at various levels using boolean operators (e.g. transposable elements, snakes, carotenoid content, Doebley). Data is exportable in spreadsheet format. This database allows to perform meta-analyses to extract global trends about the living world and the research fields. Gephebase should also help breeders, conservationists and others to identify promising target genes for crop improvement, parasite/pest control, bioconservation and genetic diagnostic. It is freely available at www.gephebase.org.

中文翻译：

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Gephebase，真核生物自然和驯化变异的基因型-表型关系数据库。

Gephebase是一个手动管理的数据库，汇集了我们对所有真核生物（主要是动物，植物和酵母）的自然，驯化和实验表型变异基础的基因和突变的累积知识。Gephebase的目的是在相对较好地支持基因型-表型关联（基于连锁图谱，关联图谱或候选基因方法）的研究中进行汇编。实验室生物中的人类临床特征和异常突变表型不包括在内，可以在其他数据库中找到（例如OMIM，OMIA，Monarch Initiative）。Gephebase包含1700多个条目。每个条目对应给定基因的两个等位基因之间的等位基因差异及其相关的表型变化，并包含分子详细信息，分类学信息，和书目信息。用户可以使用布尔运算符（例如，可转座元素，蛇，类胡萝卜素含量，多布利（Doebley））轻松浏览条目并在各个级别执行搜索。数据可以电子表格格式导出。该数据库允许执行荟萃分析，以提取有关生活世界和研究领域的全球趋势。Gephebase还应帮助育种者，保护主义者和其他人确定有前途的目标基因，用于作物改良，寄生虫/害虫控制，生物保护和遗传诊断。可从www.gephebase.org免费获得。该数据库允许执行荟萃分析，以提取有关生活世界和研究领域的全球趋势。Gephebase还应帮助育种者，保护主义者和其他人找出有前途的目标基因，用于作物改良，寄生虫/害虫控制，生物保护和遗传诊断。可从www.gephebase.org免费获得。该数据库允许执行荟萃分析，以提取有关生活世界和研究领域的全球趋势。Gephebase还应帮助育种者，保护主义者和其他人找出有前途的目标基因，用于作物改良，寄生虫/害虫控制，生物保护和遗传诊断。可从www.gephebase.org免费获得。