Landmarks in vaginal mesh development: polypropylene mesh for treatment of SUI and POP.,Nature Reviews Urology

当前位置： X-MOL 学术 › Nat. Rev. Urol. › 论文详情

Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)

Landmarks in vaginal mesh development: polypropylene mesh for treatment of SUI and POP.
Nature Reviews Urology ( IF 12.1 ) Pub Date : 2019-09-23 , DOI: 10.1038/s41585-019-0230-2
Naşide Mangir _{1,

2} , Betül Aldemir Dikici ₁ , Christopher R Chapple ₂ , Sheila MacNeil ₁

Affiliation

Vaginal meshes used in the treatment of stress urinary incontinence (SUI) and pelvic organ prolapse (POP) have produced highly variable outcomes, causing life-changing complications in some patients while providing others with effective, minimally invasive treatments. The risk:benefit ratio when using vaginal meshes is a complex issue in which a combination of several factors, including the inherent incompatibility of the mesh material with some applications in pelvic reconstructive surgeries and the lack of appropriate regulatory approval processes at the time of the premarket clearance of these products, have contributed to the occurrence of complications caused by vaginal mesh. Surgical mesh used in hernia repair has evolved over many years, from metal implants to knitted polymer meshes that were adopted for use in the pelvic floor for treatment of POP and SUI. The evolution of the material and textile properties of the surgical mesh was guided by clinical feedback from hernia repair procedures, which were also being modified to obtain the best outcomes with use of the mesh. Current evidence shows how surgical mesh fails biomechanically when used in the pelvic floor and materials with improved performance can be developed using modern material processing and tissue engineering techniques.

中文翻译：

阴道网片发展的里程碑：用于治疗SUI和POP的聚丙烯网片。

用于治疗压力性尿失禁（SUI）和盆腔器官脱垂（POP）的阴道网产生了高度可变的结果，在某些患者中改变了生活，并为其他患者提供了有效的，微创治疗方法。使用阴道网片时的风险：收益比是一个复杂的问题，其中综合了多种因素，包括网片材料固有的不相容性以及在盆腔重建手术中的某些应用以及上市前缺乏适当的监管批准程序这些产品的清除，都助长了阴道网引起的并发症的发生。用于疝气修补的外科手术网已经发展了许多年，从金属植入物到编织的聚合物网状物，这些材料被用于骨盆底中，用于处理POP和SUI。疝修补程序的临床反馈指导了外科网片的材料和纺织品性能的演变，并且对该信息进行了修改，以通过使用网片获得最佳效果。目前的证据表明，手术网在用于骨盆底时如何在生物力学上失效，可以使用现代材料加工和组织工程技术来开发性能得到改善的材料。

更新日期：2019-09-23

点击分享查看原文

点击收藏

公开下载

阅读更多本刊最新论文本刊介绍/投稿指南11