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4 Ds in health research-working together toward rapid precision medicine.
EMBO Molecular Medicine ( IF 9.0 ) Pub Date : 2019-09-18 , DOI: 10.15252/emmm.201910917
Ellen Niederberger 1 , Michael J Parnham 2, 3 , Jochen Maas 4 , Gerd Geisslinger 1, 2, 3
Affiliation  

Patient therapy is based mainly on a combination of diagnosis, suitable monitoring or support devices and drug treatment and is usually employed for a pre-existing disease condition. Therapy remains predominantly symptom-based, although it is increasingly clear that individual treatment is possible and beneficial. However, reasonable precision medicine can only be realized with the coordinated use of diagnostics, devices and drugs in combination with extensive databases (4Ds), an approach that has not yet found sufficient implementation. The practical combination of 4Ds in health care is progressing, but several obstacles still hamper their extended use in precision medicine.

中文翻译:


健康研究领域的 4 个 D——共同努力实现快速精准医学。



患者治疗主要基于诊断、合适的监测或支持设备以及药物治疗的组合,通常用于治疗已有的疾病。尽管越来越清楚个体化治疗是可能且有益的,但治疗仍然主要基于症状。然而,合理的精准医疗只能通过诊断、设备和药物与广泛数据库(4D)的协调使用来实现,这种方法尚未得到充分实施。 4D 在医疗保健中的实际结合正在取得进展,但仍存在一些障碍阻碍其在精准医疗中的广泛应用。
更新日期:2019-11-07
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