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IL-13 mRNA Tissue Content Identifies Two Subsets of Adult Ulcerative Colitis Patients With Different Clinical and Mucosa-Associated Microbiota Profiles
Journal of Crohn's and Colitis ( IF 8.3 ) Pub Date : 2019-09-10 , DOI: 10.1093/ecco-jcc/jjz154
Alessia Butera 1 , Monica Di Paola 2 , Francesco Vitali 3 , Daniela De Nitto 4 , Francesco Covotta 5 , Francesco Borrini 6 , Roberta Pica 4 , Carlotta De Filippo 3 , Duccio Cavalieri 2 , Alessandro Giuliani 7 , Annamaria Pronio 5 , Monica Boirivant 1
Affiliation  

A personalized approach to therapy hold great promise to improve disease outcomes. To this end, the identification of different subsets of patients according to the prevalent pathogenic process might guide the choice of therapeutic strategy. We hypothesize that ulcerative colitis [UC] patients might be stratified according to distinctive cytokine profiles and/or to a specific mucosa-associated microbiota.

中文翻译:

IL-13 mRNA组织含量确定具有不同临床和与粘膜相关的微生物群特征的成人溃疡性结肠炎患者的两个亚集

个性化的治疗方法有望改善疾病的预后。为此,根据普遍的致病过程识别不同的患者亚组可能会指导治疗策略的选择。我们假设溃疡性结肠炎[UC]患者可能会根据独特的细胞因子谱和/或特定的黏膜相关微生物群而分层。
更新日期:2020-04-17
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