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Comment on “Acetylcysteine in paracetamol poisoning: a perspective of 45 years of use” by D. N. Bateman and J. W. Dear, Toxicol. Res., 2019, 8, 489
Toxicology Research ( IF 2.2 ) Pub Date : 2019-09-11 , DOI: 10.1039/c9tx00158a
Michael E. Mullins 1 , Mark C. Yarema 2 , Marco L. A. Sivilotti 3 , Margaret Thompson 4 , D. Adam Algren 5 , Michael C. Beuhler 6 , Christopher P. Holstege 7
Affiliation  

We point out an acetylcysteine protocol that a previous article (D. N. Bateman and J. W. Dear, Toxicol. Res., 2019, 8, 489–498) overlooked. The standard concentration protocol uses a uniform concentration of 30 mg mL−1 for all patients to reduce errors in preparation and administration. Usually a single 1 L bag is sufficient for most patients. Various centers in the US and Canada use this approach.

中文翻译:

DN Bateman和JW Dear,Toxicol对“对乙酰氨基酚中毒中的乙酰半胱氨酸:45年使用的前景”发表评论。Res。,2019,8,489

我们指出乙酰半胱氨酸协议,先前的文章(DN贝特曼和JW亲爱的,毒理学,RES。,2019年,8,489-498)忽视。标准浓度方案对所有患者使用30 mg mL -1的统一浓度,以减少制备和给药中的错误。通常,对于大多数患者来说,一个1 L的袋子就足够了。美国和加拿大的各个中心都使用这种方法。
更新日期:2019-09-11
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