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Individually Customized IOL Versus Standard Spherical Aberration-Correcting IOL.
Journal of Refractive Surgery ( IF 2.9 ) Pub Date : 2019-09-01 , DOI: 10.3928/1081597x-20190814-02
Jens Schrecker , Simon Schröder , Achim Langenbucher , Berthold Seitz , Timo Eppig

PURPOSE To compare the visual performance of an individually customized intraocular lens (IOL) versus a standard spherical aberration-correcting IOL. METHODS In this prospective comparative study, 74 eyes of 60 patients scheduled for cataract surgery were randomized in a 2:1 ratio to receive either an individually customized IOL (; HumanOptics AG, Erlangen, Germany; customized group) or an aspheric IOL with a standard correction of spherical aberration (SA) (Tecnis ZCB00; Johnson & Johnson Vision Surgical, Inc., Santa Ana, CA; standardized group). In the customized group, IOL calculation was based on a minimum of a merit function that contained terms representing residual refraction, residual SA, and modulation transfer function. In the standardized group, the IOL was calculated with a routine procedure using the Holladay formula and had a standard SA correction of -0.27 µm. Refraction, visual acuity (far, intermediate, near), photopic and mesopic contrast sensitivity, defocus curve, corneal and ocular spherical aberration, and pupil size were measured 4 weeks and 3 months postoperatively. RESULTS The customized group comprised 48 eyes of 37 patients and the standardized group 26 eyes of 23 patients. At 3 months, mean total ocular SA (5 mm) was 0.04 ± 0.06 µm in the customized group and -0.01 ± 0.05 µm in the standardized group. Uncorrected distance visual acuity and distance-corrected near visual acuity were statistically significantly better in the customized group. Contrast sensitivity testing yielded significantly better results in the customized group under photopic and mesopic conditions for almost all spatial frequencies. Compared to the standardized group, the defocus curve of the customized group showed a wider plateau surrounding the distance focal point. CONCLUSIONS With the implantation of an individually optimized aspheric IOL visual performance, especially contrast sensitivity, can be significantly improved compared to a standard aberration-correcting IOL. [J Refract Surg. 2019;35(9):565-574.].

中文翻译:

个性化定制的IOL与标准的球差校正IOL。

目的比较单独定制的人工晶状体(IOL)与标准球面像差校正IOL的视觉性能。方法在这项前瞻性比较研究中,按计划将白内障手术的60例患者中的74眼按2:1的比例随机分配,以接受单独定制的IOL(;德国埃尔兰根的HumanOptics AG;定制组)或标准的非球面IOL矫正球面像差(SA)(Tecnis ZCB00;美国加利福尼亚州圣安娜的Johnson&Johnson Vision Surgical,Inc .;标准化组)。在定制组中,IOL计算基于包含代表残余折射,残余SA和调制传递函数的项的优点函数的最小值。在标准化组中 IOL是使用Holladay公式按常规程序计算的,标准SA校正值为-0.27 µm。术后4周和3个月测量屈光度,视敏度(远,中,近),明视和中视对比敏感度,散焦曲线,角膜和眼球差和瞳孔大小。结果定制组包括37例患者的48眼,标准化组包括23例患者的26眼。在3个月时,定制组平均眼总SA(5 mm)为0.04±0.06 µm,标准化组为-0.01±0.05 µm。定制组的未矫正远视力和远矫正近视力在统计学上显着更好。在几乎所有空间频率的明视和中视条件下,对比灵敏度测试在定制组中产生了明显更好的结果。与标准化组相比,定制组的散焦曲线在距离焦点周围显示出更宽的平台。结论与标准的像差校正IOL相比,通过植入单独优化的非球面IOL可以显着改善视觉性能,尤其是对比度灵敏度。[J Refract Surg。2019; 35(9):565-574。]。与标准像差校正IOL相比,可以显着改善。[J Refract Surg。2019; 35(9):565-574。]。与标准像差校正IOL相比,可以显着改善。[J Refract Surg。2019; 35(9):565-574。]。
更新日期:2019-09-11
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