Environmental factors are poorly understood in the etiology of Alzheimer's disease (AD) and related dementias. The importance of environmental factors in gene environment interactions (GxE) is suggested by wide individual differences in cognitive loss, even for carriers of AD‐risk genetic variants.

中文翻译：

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阿尔茨海默病暴露组


环境因素对于阿尔茨海默病（AD）和相关痴呆症的病因学知之甚少。认知损失的巨大个体差异表明环境因素在基因环境相互作用（GxE）中的重要性，即使对于 AD 风险遗传变异的携带者也是如此。