The nanoarchitectonics concept enables us to produce functional systems and materials from nano-scale units through nanotechnological approaches together with the processes including chemical syntheses, atom/molecule manipulations, self-assemblies, self-organizations, field-induced material regulations, and bio-related processes. Especially, manipulations of molecules (molecular machines) and sophisticated organization would be attractive targets in interfacial nanoarchitectonics. In this short review, we introduce several typical examples on manipulations of functional molecules and molecular machines at interfacial media. The examples are classified roughly according to driving forces of manipulations; (i) manipulations through chemical reactions and interactions; (ii) light-driven manipulations; (iii) electrically controlled manipulations; (iv) mechanical manipulations. Future possibilities of molecular manipulations at interfaces such as usages in biological systems are discussed in perspective section.

纳米建筑学的概念使我们能够通过纳米技术方法，从纳米级单位生产功能性系统和材料，以及包括化学合成，原子/分子操纵，自组装，自组织，场致材料调控和生物相关的过程流程。特别地，在界面纳米建筑学中，分子的操作（分子机器）和复杂的组织将是有吸引力的目标。在这篇简短的评论中，我们介绍了一些在界面介质上操纵功能分子和分子机器的典型例子。这些示例大致根据操作的驱动力进行分类。（i）通过化学反应和相互作用进行操纵；（ii）光驱动的操纵；（iii）电控操纵；（iv）机械操纵。透视部分讨论了在界面上进行分子操作（如在生物系统中的用途）的未来可能性。