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Danish experience of meticillin-resistant Staphylococcus aureus eradication with emphasis on nose-throat colonization and supplementary systemic antibiotic treatment
Journal of Hospital Infection ( IF 3.9 ) Pub Date : 2019-09-09 , DOI: 10.1016/j.jhin.2019.09.005
I.S. Petersen , J.M. Christensen , A.B. Zeuthen , P.B. Madsen

The study-aim was to evaluate the Danish national Board of Health's guidance for treating MRSA carriage focusing on MRSA nose-throat carriage and use of supplementary systemic antibiotics. We analyze results of MRSA eradication treatment of 358 patients, focusing on those with nose (n=58) or throat (n=183) MRSA colonization. We found that the Danish guidance for treating MRSA have greater success for patients with nose colonization (66%) compared to throat colonization (41%), even though the cumulative eradication rates were equal after additional three treatment cycles (71% versus 73%). We find no positive effect of supplementing the colonization treatment with systemic antibiotics.



中文翻译:

丹麦根除耐甲氧西林金黄色葡萄球菌的经验,侧重于鼻咽定植和补充全身抗生素治疗

该研究的目的是评估丹麦国家卫生委员会关于治疗MRSA支架的指南,重点是MRSA鼻咽支架和补充全身性抗生素的使用。我们分析了358例MRSA根除治疗的结果,重点是鼻(n = 58)或咽喉(n = 183)MRSA定植的患者。我们发现,即使在另外三个疗程后累积根除率相同(71%比73%),丹麦的MRSA治疗指南对于鼻部定植(66%)的患者,也比喉部定植(41%)的患者更为成功。 。我们发现用全身性抗生素补充定植治疗没有积极作用。

更新日期:2019-09-09
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