I never understood the lyrics of Sly and the Family Stone's 1971 hit It's a Family Affair (even after reading Sly's explanation). But it's playing in my head, getting in the way of my mulling over what Anne Cross, Professor of Neurology and Section Head of Neuroimmunology at Washington University School of Medicine (St. Louis, Missouri, USA), didn't tell me in the notes she sent over for her Profile. She has recently been awarded the 2019 John Dystel Prize, a garland bestowed by the US National Multiple Sclerosis Society and the American Academy of Neurology for lifetime achievements in research into multiple sclerosis. Yet she has given me under a line on this. And there are just four lines describing her entire research effort on B cells and multiple sclerosis. Wasn't it a huge deal when she was among the first to demonstrate the crucial role they play in disease progression? I imagine she's going to tell me about the flack she must have taken when everyone else was focusing on T cells. But there's nothing. And wasn't it she who pioneered B cell depletion therapy? I remember reading somewhere that it reduced MRI activity of the disease by around 88% in patients failing on everything else available at the time, and that it led to the approval of a B cell-depleting antibody treatment. I check. It was her; it's partly why she got the prize. I rummage through her notes again. There's nothing—rather, she tells me she has a rescue dog. “They are the best dogs imaginable”, she writes. “My daughter has two!” I find myself writing back as if she were my sister, telling her I have a rescue cat. What is wrong with me? She tells me she'd love to have two or three cats, but that she's allergic. And that song just won't go away.

中文翻译：

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安妮·克罗斯（Anne Cross）：这是家庭事务。

我从没听过Sly and the Family Stone 1971年的热门单曲It's a Family Affair（即使在阅读了Sly的解释之后）。但是它正在我的脑海中发挥作用，阻碍了我对华盛顿大学医学院神经病学教授和神经免疫学部门负责人安妮·克罗斯（Anne Cross）没有告诉我的事情的思考。她为自己的个人资料发送过来的笔记。她最近获得了2019年约翰·戴斯泰尔奖（John Dystel Prize），这是一项由美国国家多发性硬化症学会和美国神经科学院颁发的花环，以表彰其对多发性硬化症的终生研究成就。然而，她在这件事上给了我一点意见。仅有四行内容描述了她在B细胞和多发性硬化症方面的全部研究工作。当她是第一个证明他们在疾病进展中起关键作用的人时，这不是一笔大数目吗？我想她 告诉我其他人都专注于T细胞时她必须采取的弹跳动作。但是什么都没有。是不是率先开展B细胞耗竭疗法的她吗？我记得在某处读过一篇文章，该书在当时无法进行的所有其他操作均失败的患者中，使该疾病的MRI活性降低了约88％，并导致批准了消耗B细胞的抗体治疗。我查一下 是她 这是她获得奖金的部分原因。我再次翻遍她的笔记。什么都没有-而是，她告诉我她有一只救狗。她写道：“它们是可以想象的最好的狗”。“我的女儿有两个！” 我发现自己在回信，好像她是我的妹妹一样，告诉她我有一只救命猫。我是怎么了？她告诉我她很想养两只或三只猫，但是她很过敏。那首歌只会赢