The effects of aqueous extraction of bioactive compounds from pomegranate peels using conventional extraction (CE) and extraction assisted by infrared irradiation (IR), ultrasound (US), pulsed electric fields (PEF), and high-voltage electrical discharges (HVED) have been compared. For the extractions assisted by US, PEF and HVED, the saturation in extraction was observed approximately at the same specific energy input in the order of W ≈ 90–100 kJ/kg. HVED assisted extraction enhanced the recovery of polyphenols by ≈3 and ≈1.3 times as compared to US and PEF assisted extractions, respectively. Scanning electron microscopy (SEM) data evidenced that the highest yield of total polyphenols after the HVED treatment can reflect the presence of a strong damage of the microstructure of pomegranate skins. The obtained data on inhibition of growth of A. flavus and biosynthesis of aflatoxin B1 were explained accounting for the presence of different synergetic effects of phenolic compounds on inhibition of different bioactivities. All the studied extracts (0.2 mg/mL) demonstrated the higher inhibition efficiency for S. aureus (up to ≈80%) as compared to E. coli (up to ≈33%). PEF selectively extracted and enhanced the recovery of ellagic acid (≈740 μg/g DM), whereas HVED (≈345 μg/g DM) intensified gallic acid extraction compared to US, IR, HVED and WB.

使用常规提取（CE）并通过红外辐射（IR），超声（US），脉冲电场（PEF）和高压放电（HVED）辅助提取从石榴皮中水提取生物活性化合物的效果已得到证实比较的。对于US，PEF和HVED辅助的萃取，在相同的比能量输入下，以W的量级观察到萃取的饱和度 ≈90–100 kJ / kg。HVED辅助萃取与US和PEF辅助萃取相比，分别将多酚的回收率提高了约3倍和≈1.3倍。扫描电子显微镜（SEM）数据表明，HVED处理后总多酚的最高收率可以反映出石榴皮微观结构的强烈破坏。解释了获得的有关黄曲霉生长的抑制和黄曲霉毒素B1的生物合成的数据，这说明了酚类化合物对不同生物活性的抑制具有不同的协同作用。与大肠杆菌相比，所有研究的提取物（0.2 mg / mL）均显示出对金黄色葡萄球菌的更高抑制效率（最高≈80％）（高达≈33％）。PEF有选择地提取鞣花酸（约740μg/ g DM）并提高了回收率，而HVED（≈345μg/ g DM）与US，IR，HVED和WB相比增强了没食子酸的提取。