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A review of bioanalytical techniques for evaluation of cannabis (Marijuana, weed, Hashish) in human hair
BMC Chemistry ( IF 4.3 ) Pub Date : 2019-08-14 , DOI: 10.1186/s13065-019-0627-2
Iltaf Shah , Bayan Al-Dabbagh , Alaa Eldin Salem , Saber A.A. Hamid , Neak Muhammad , Declan P. Naughton

Cannabis products (marijuana, weed, hashish) are among the most widely abused psychoactive drugs in the world, due to their euphorigenic and anxiolytic properties. Recently, hair analysis is of great interest in analytical, clinical, and forensic sciences due to its non-invasiveness, negligible risk of infection and tampering, facile storage, and a wider window of detection. Hair analysis is now widely accepted as evidence in courts around the world. Hair analysis is very feasible to complement saliva, blood tests, and urinalysis. In this review, we have focused on state of the art in hair analysis of cannabis with particular attention to hair sample preparation for cannabis analysis involving pulverization, extraction and screening techniques followed by confirmatory tests (e.g., GC–MS and LC–MS/MS). We have reviewed the literature for the past 10 years’ period with special emphasis on cannabis quantification using mass spectrometry. The pros and cons of all the published methods have also been discussed along with the prospective future of cannabis analysis.

中文翻译:

评估人发中大麻(大麻,杂草,大麻)的生物分析技术的综述

大麻产品(大麻,杂草,大麻)由于具有欣快感和抗焦虑特性,因此是世界上滥用最广泛的精神药物。最近,由于头发分析的非侵入性,可忽略的感染和篡改风险,方便的存储方式以及更广阔的检测范围,因此在分析,临床和法医学领域引起了极大的兴趣。如今,头发分析已被世界各地的法院广泛接受为证据。头发分析对补充唾液,血液检查和尿液分析非常可行。在这篇综述中,我们集中于大麻头发分析的最新技术,特别关注用于大麻分析的头发样品制备,包括粉化,提取和筛选技术,然后进行确认性测试(例如GC-MS和LC-MS / MS)。 )。我们回顾了过去10年的文献,特别侧重于使用质谱定量大麻。还讨论了所有已发布方法的优缺点,以及大麻分析的未来前景。
更新日期:2019-08-14
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