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A Non-Enzymatic Glucose Sensor Based on the Hybrid Thin Films of Cu on Acetanilide/ITO
Journal of The Electrochemical Society ( IF 3.1 ) Pub Date : 2019-08-13 , DOI: 10.1149/2.0231913jes
Maryam Sajadpour 1 , Hossein Siampour 1 , Sara Abbasian 2 , Masoud Amiri 3 , Raffael Rameshan 4 , Christoph Rameshan 4 , Ali Hajian 5 , Hasan Bagheri 6 , Ahmad Moshaii 1
Affiliation  

A stable and sensitive non-enzymatic glucose sensor is proposed based on the hybrid thin films of copper on acetanilide/ITO-PET. The electrode was fabricated through a two-step synthesis process including electrochemical deposition of acetanilide on ITO-PET, subsequent by physical vapor deposition of a copper film. The electron microscopy images showed the formation of a porous structure on the ITO-PET sheet. Such modified electrode presents a high sensitivity of 59.95μAmM−1cm−2 with a low limit of detection of 1.501μM. This glucose sensor exhibits a range of linear response between 2 to 12mM. In addition, it includes a variety of advantages as high flexibility, the possibility for scale-up production, low material consumption, low cost, excellent reproducibility, high selectivity, good sensitivity and short response time. Finally, the glucose determination of different human blood serums indicates that the deviation of this sensor from the clinical measurements is less than 5%.

中文翻译:

基于乙酰苯胺/ ITO上Cu杂化薄膜的非酶葡萄糖传感器

基于铜在乙酰苯胺/ ITO-PET上的杂化薄膜,提出了一种稳定,灵敏的非酶葡萄糖传感器。电极是通过两步合成工艺制造的,包括在ITO-PET上电化学沉积乙酰苯胺,然后进行物理气相沉积铜膜。电子显微镜图像显示在ITO-PET片上形成多孔结构。这样的修饰电极表现出59.95μAmM -1 cm -2的高灵敏度。最低检测限为1.501μM。该葡萄糖传感器的线性响应范围在2至12mM之间。此外,它还具有多种优势,例如灵活性高,可按比例放大生产,材料消耗低,成本低,可重复性好,选择性高,灵敏度高和响应时间短。最后,对不同人血清的葡萄糖测定表明该传感器与临床测量值的偏差小于5%。
更新日期:2019-08-14
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