BACKGROUND The study aimed (1) to assess the prognostic value of three-dimensional echocardiography (3DE) derived right ventricular (RV) ejection fraction (EF) and (2) to evaluate relative prognostic importance of reduced and preserved left ventricular (LV) EF and RVEF to predict all-cause mortality and cardiac death in a large cohort of patients with cardiac diseases. METHODS LV and RV volumes and EF were assessed by 3DE in 394 patients with various cardiovascular diseases. Patients were divided into four groups: (1) normal LVEF (≥50%) and normal RVEF (≥45%), n = 183; (2) reduced LVEF (<50%) and normal RVEF (≥45%), n = 75; (3) normal LVEF (≥50%) and reduced RVEF (<45%), n = 61; (4) reduced LVEF (<50%) and reduced RVEF (<45%), n = 75. The patients were followed up for 3.7 ± 1.1 years. RESULTS Reduced 3DE-derived RVEF was associated with all-cause mortality (P < .0001). The four groups had significantly different survival (P < .0001). Both all-cause mortality and cardiac death in patients with reduced RVEF and normal LVEF were significantly higher than in those with reduced LVEF and normal RVEF (P = .0007 and P = .0091, respectively) and did not differ significantly from patients with reduced EF of both ventricles (P = .2198 and P = .0846, respectively). CONCLUSIONS Reduced 3DE-derived RVEF was associated with all-cause mortality and cardiac death in patients with various cardiovascular diseases. Impairment of RVEF carried a significantly higher risk of mortality independent of LVEF.

中文翻译：

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心脏病患者左，右心室射血分数的相对预后重要性。

背景研究旨在（1）评估三维超声心动图（3DE）衍生的右心室（RV）射血分数（EF）的预后价值，以及（2）评估减少和保留左心室（LV）EF的相对预后重要性和RVEF预测大量心脏病患者的全因死亡率和心源性死亡。方法采用3DE技术对394例心血管疾病患者的LV，RV和EF进行评估。患者分为四组：（1）正常LVEF（≥50％）和正常RVEF（≥45％），n = 183；（2）LVEF（<50％）和正常RVEF（≥45％）降低，n = 75；（3）正常LVEF（≥50％）和RVEF降低（<45％），n = 61；（4）LVEF降低（<50％）和RVEF降低（<45％），n =75。对患者进行了3.7±1.1年的随访。结果3DE引起的RVEF降低与全因死亡率相关（P <.0001）。四个组的生存率差异显着（P <.0001）。RVEF降低和LVEF正常的患者的全因死亡率和心源性死亡均显着高于LVEF和RVEF降低的患者（分别为P = .0007和P = .0091），与LVEF和LVEF降低的患者无明显差异两个心室的EF（分别为P = .2198和P = .0846）。结论降低3DE衍生的RVEF与各种心血管疾病患者的全因死亡率和心源性死亡有关。与LVEF无关，RVEF的受损具有更高的死亡风险。RVEF降低和LVEF正常的患者的全因死亡率和心源性死亡均显着高于LVEF和RVEF降低的患者（分别为P = .0007和P = .0091），与LVEF和LVEF降低的患者无明显差异两个心室的EF（分别为P = .2198和P = .0846）。结论降低3DE衍生的RVEF与各种心血管疾病患者的全因死亡率和心源性死亡有关。与LVEF无关，RVEF的受损具有更高的死亡风险。RVEF降低和LVEF正常的患者的全因死亡率和心源性死亡均显着高于LVEF降低和RVEF正常的患者（分别为P = .0007和P = .0091），与LVEF和LVEF降低的患者无明显差异两个心室的EF（分别为P = .2198和P = .0846）。结论降低3DE衍生的RVEF与各种心血管疾病患者的全因死亡率和心源性死亡有关。与LVEF无关，RVEF的受损具有更高的死亡风险。结论降低3DE衍生的RVEF与各种心血管疾病患者的全因死亡率和心源性死亡有关。与LVEF无关，RVEF的受损具有更高的死亡风险。结论降低3DE衍生的RVEF与各种心血管疾病患者的全因死亡率和心源性死亡有关。与LVEF无关，RVEF的受损具有更高的死亡风险。